Voodoo Extreme has a nifty page up detailing their 37 hour exploit into Fallout 3. There are tons of screenshots and videos for your viewing pleasure here.
Thirty-seven hours in, I've become a vampire, been hailed a saviour, a
bigot, and a lover extraordinaire. I've battled Super Mutants,
Radscorpions, and all manner of nasties. I've left the safety and
security of the Vault, I've exterminated those who opposed me. And yet,
I've only scratched the surface.