Gaming Nexus has posted their E3 impressions of Fallout 3.
On music:
A lot of the art and music will be familiar to Fallout fans so don't fear as the property is in good hands.
On visual effects:
So much little detail in what I saw made the world come alive. One
impressive effect was the passing of some sand and dirt in the wind as
you looked around. The mutants exhibit great detail as well with some
very nice motion capture. Havok is working overtime here generating
dynamic movement.