Desslock, from PC Gamer, recently replied to a post by Briosafreak over at the QTT forums with some very interesting information.
Briosafreak: On a final note
there seems to be a few doubts on how the game will turn out. First
person and Real Time combat are locked, there's no way to change that
Desslock: All I'll say is that you are wrong.
Now, as we know, Desslock had a visit to the Bethesda studios a while back. He saw a bunch of Fallout 3 stuff while he was there, confirming East coast locations. We know that he's been there, and that he's seen things, so it's logical to assume he has intel on this.